产品货号:
GS4557
中文名称:
重组猴S100B
英文名称:
Recombinant Rhesus Macaque S100 Calcium Binding Protein B
产品规格:
2μg
发货周期:
1~3天
产品价格:
询价
分子量:Approximately 10.6kDa,a single non-glycosylated polypeptide chain containing 91 amino acids
储存条件:冷冻(-20℃)
概述
S100B belongs to the S100 family,which containing 2 EF-hand calcium-binding motifs.In humans,S100B protein is encoded by the S100P gene located at 4q16,but genes that encode other numbers of s100 family proteins are almost located at 1q21 as a cluster.S100B is glial-specific and is expressed primarily by astrocytes.Not all astrocytes express S100B.It has been shown that S100B is only expressed by a subtype of mature astrocytes that ensheath blood vessels and by NG2-expressing cells.This protein may function in neurite extension,proliferation of melanoma cells,stimulation of Ca2+ fluxes,inhibition of PKC-mediated phosphorylation,astrocytosis and axonal proliferation,and inhibition of microtubule assembly.In the developing CNS it acts as a neurotrophic factor and neuronal survival protein.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索:重组猴S100B,S100B, Monkey
储存条件:冷冻(-20℃)
概述
S100B belongs to the S100 family,which containing 2 EF-hand calcium-binding motifs.In humans,S100B protein is encoded by the S100P gene located at 4q16,but genes that encode other numbers of s100 family proteins are almost located at 1q21 as a cluster.S100B is glial-specific and is expressed primarily by astrocytes.Not all astrocytes express S100B.It has been shown that S100B is only expressed by a subtype of mature astrocytes that ensheath blood vessels and by NG2-expressing cells.This protein may function in neurite extension,proliferation of melanoma cells,stimulation of Ca2+ fluxes,inhibition of PKC-mediated phosphorylation,astrocytosis and axonal proliferation,and inhibition of microtubule assembly.In the developing CNS it acts as a neurotrophic factor and neuronal survival protein.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
纯度 | >97%by SDS-PAGE and HPLC analyses. |
来源 | Escherichia coli. |
生物活性 | Data Not Available. |
成分 | Lyophilized from a 0.2μmfiltered solution in PBS,pH 7.4. |
内毒素 | Less than 1 EU/μg of rRhS100B as determined by LAL method. |
复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
氨基酸序列 | SELEKAMVAL IDVFHQYSGR EGDKHKLKKS ELKELINNEL SHFLEEIKEQ EVVDKVMETL DSDGDGECDF QEFMAFVAMV TTACHEFFEH E |
相关搜索:重组猴S100B,S100B, Monkey